Histochemical demonstration of enhanced glutathione content in enzyme-altered islands induced by carcinogens in rat liver.
نویسندگان
چکیده
The presence of glutathione was demonstrated histochemically in livers of rats treated with diethylnitrosamine or N-nitrosomorpholine. Glutathione content was markedly elevated in adenosine triphosphatase-deficient, gamma-glutamyltranspeptidase-positive hyperplastic cell islands. This finding may partly explain the increased resistance of hyperplastic cells to cytotoxic actions of hepatocarcinogens.
منابع مشابه
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عنوان ژورنال:
- Cancer research
دوره 40 2 شماره
صفحات -
تاریخ انتشار 1980